Photodynamic inactivation of Escherichia coli by methylene blue incorporated in ZSM-5 zeolite channels under red LED light

نویسندگان

  • Miroslava Smolinská
  • Petra Olejníková
  • Daniela Hudecová
  • Gabriel Čík
چکیده

Photodynamic therapy (PDT) is a method that combines the use of nontoxic components, namely photosensitizer, light and oxygen to cause localised oxidative photo-induced damage. The aim of this study was to contribute to PDT development by studying an alternative light sources using red light-emitting diode (LED) light and evaluated its effect on the photodynamic activity of methylene blue (MB) in biological experiments. To prepare a new heterogeneous photocatalyst by incorporating the MB into ZSM-5 zeolite structures, which effectively produces ROS by photoactivation with visible light. The investigations of the effectiveness of PDT with red LED light and MB, afterwards with ZSM-5-MB were carried out on Gram-negative bacteria Escherichia coli CCM 3988.

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تاریخ انتشار 2010